An investigation into cockpit display developments in the general aviation aircraft fleet

As we have progressed into the 21st Century, the general aviation (GA) cockpit has been slow to evolve to keep pace with the advances in technology and research that have been applied to the avionics displays for military and civil commercial aviation applications. GA cockpits are just now beginning to reflect the benefits of these advances The increased use of human factors research in the design of GA avionics displays has led to the awareness of the importance of improved information presentation and data cueing As a result, instrument panels are integrating a variety of highly configurable electronic, full-color, hierarchical in design, multifunction displays (MFD) These MFDs are being utilized for inserting a significant increase of coded and processed information into the often display-cluttered aircraft cockpit for use by the GA pilot. MFDs, coded and formatted properly, can aid the GA pilot in an overall increase in situational awareness (SA) of both the aircraft\u27s performance and the surrounding flight environment. In addition, many of these new MFDs have the capability to combine and integrate multiple data inputs onto a single display sometimes referred to as Data Fusion. In a similar vein, as “data fused” MFDs proliferate, the number of single functionality avionics system displays and control boxes can be reduced and replaced by MFD systems with multiple roles and capabilities. This will increase the available instrument panel space for additional or redundant components This thesis will investigate applicable human factors research and see how advanced GA avionics technologies are evolving as a result. This thesis will also discuss systems that should be incorporated in GA aircraft to improve SA for pilots in the GA aircraft sector

Using [C II] 158 μm Emission from Isolated ISM Phases as a Star Formation Rate Indicator

The brightest observed emission line in many star-forming galaxies is the [C II] 158 μm line, making it detectable up to z ~ 7. In order to better understand and quantify the [C II] emission as a tracer of star formation, the theoretical ratio between the [N II] 205 μm emission and the [C II] 158 μm emission has been employed to empirically determine the fraction of [C II] emission that originates from the ionized and neutral phases of the interstellar medium (ISM). Sub-kiloparsec measurements of the [C II] 158 μm and [N II] 205 μm lines in nearby galaxies have recently become available as part of the Key Insights in Nearby Galaxies: a Far Infrared Survey with Herschel (KINGFISH) and Beyond the Peak programs. With the information from these two far-infrared lines along with the multi-wavelength suite of KINGFISH data, a calibration of the [C II] emission line as a star formation rate (SFR) indicator and a better understanding of the [C II] deficit are pursued. [C II] emission is also compared to polycyclic aromatic hydrocarbon (PAH) emission in these regions to compare photoelectric heating from PAH molecules to cooling by [C II] in the neutral and ionized phases of the ISM. We find that the [C II] emission originating in the neutral phase of the ISM does not exhibit a deficit with respect to the infrared luminosity and is therefore preferred over the [C II] emission originating in the ionized phase of the ISM as an SFR indicator for the normal star-forming galaxies included in this sample

Using [C II] 158 μm Emission from Isolated ISM Phases as a Star Formation Rate Indicator

The brightest observed emission line in many star-forming galaxies is the [C II] 158 μm line, making it detectable up to z ~ 7. In order to better understand and quantify the [C II] emission as a tracer of star formation, the theoretical ratio between the [N II] 205 μm emission and the [C II] 158 μm emission has been employed to empirically determine the fraction of [C II] emission that originates from the ionized and neutral phases of the interstellar medium (ISM). Sub-kiloparsec measurements of the [C II] 158 μm and [N II] 205 μm lines in nearby galaxies have recently become available as part of the Key Insights in Nearby Galaxies: a Far Infrared Survey with Herschel (KINGFISH) and Beyond the Peak programs. With the information from these two far-infrared lines along with the multi-wavelength suite of KINGFISH data, a calibration of the [C II] emission line as a star formation rate (SFR) indicator and a better understanding of the [C II] deficit are pursued. [C II] emission is also compared to polycyclic aromatic hydrocarbon (PAH) emission in these regions to compare photoelectric heating from PAH molecules to cooling by [C II] in the neutral and ionized phases of the ISM. We find that the [C II] emission originating in the neutral phase of the ISM does not exhibit a deficit with respect to the infrared luminosity and is therefore preferred over the [C II] emission originating in the ionized phase of the ISM as an SFR indicator for the normal star-forming galaxies included in this sample

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

Background Non-alcoholic steatohepatitis (NASH) is a common type of chronic liver disease that can lead to cirrhosis. Obeticholic acid, a farnesoid X receptor agonist, has been shown to improve the histological features of NASH. Here we report results from a planned interim analysis of an ongoing, phase 3 study of obeticholic acid for NASH. Methods In this multicentre, randomised, double-blind, placebo-controlled study, adult patients with definite NASH,non-alcoholic fatty liver disease (NAFLD) activity score of at least 4, and fibrosis stages F2–F3, or F1 with at least oneaccompanying comorbidity, were randomly assigned using an interactive web response system in a 1:1:1 ratio to receive oral placebo, obeticholic acid 10 mg, or obeticholic acid 25 mg daily. Patients were excluded if cirrhosis, other chronic liver disease, elevated alcohol consumption, or confounding conditions were present. The primary endpointsfor the month-18 interim analysis were fibrosis improvement (≥1 stage) with no worsening of NASH, or NASH resolution with no worsening of fibrosis, with the study considered successful if either primary endpoint was met. Primary analyses were done by intention to treat, in patients with fibrosis stage F2–F3 who received at least one dose of treatment and reached, or would have reached, the month 18 visit by the prespecified interim analysis cutoff date. The study also evaluated other histological and biochemical markers of NASH and fibrosis, and safety. This study is ongoing, and registered with ClinicalTrials.gov, NCT02548351, and EudraCT, 20150-025601-6. Findings Between Dec 9, 2015, and Oct 26, 2018, 1968 patients with stage F1–F3 fibrosis were enrolled and received at least one dose of study treatment; 931 patients with stage F2–F3 fibrosis were included in the primary analysis (311 in the placebo group, 312 in the obeticholic acid 10 mg group, and 308 in the obeticholic acid 25 mg group). The fibrosis improvement endpoint was achieved by 37 (12%) patients in the placebo group, 55 (18%) in the obeticholic acid 10 mg group (p=0·045), and 71 (23%) in the obeticholic acid 25 mg group (p=0·0002). The NASH resolution endpoint was not met (25 [8%] patients in the placebo group, 35 [11%] in the obeticholic acid 10 mg group [p=0·18], and 36 [12%] in the obeticholic acid 25 mg group [p=0·13]). In the safety population (1968 patients with fibrosis stages F1–F3), the most common adverse event was pruritus (123 [19%] in the placebo group, 183 [28%] in the obeticholic acid 10 mg group, and 336 [51%] in the obeticholic acid 25 mg group); incidence was generally mild to moderate in severity. The overall safety profile was similar to that in previous studies, and incidence of serious adverse events was similar across treatment groups (75 [11%] patients in the placebo group, 72 [11%] in the obeticholic acid 10 mg group, and 93 [14%] in the obeticholic acid 25 mg group). Interpretation Obeticholic acid 25 mg significantly improved fibrosis and key components of NASH disease activity among patients with NASH. The results from this planned interim analysis show clinically significant histological improvement that is reasonably likely to predict clinical benefit. This study is ongoing to assess clinical outcomes

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Measurement of the W gamma Production Cross Section in Proton-Proton Collisions at root s=13 TeV and Constraints on Effective Field Theory Coefficients

A fiducial cross section for W gamma production in proton-proton collisions is measured at a center-of-mass energy of 13 TeV in 137 fb(-1) of data collected using the CMS detector at the LHC. The W -> e nu and mu nu decay modes are used in a maximum-likelihood fit to the lepton-photon invariant mass distribution to extract the combined cross section. The measured cross section is compared with theoretical expectations at next-to-leading order in quantum chromodynamics. In addition, 95% confidence level intervals are reported for anomalous triple-gauge couplings within the framework of effective field theory.Peer reviewe

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.

Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

Peer reviewe

Reconstruction of signal amplitudes in the CMS electromagnetic calorimeter in the presence of overlapping proton-proton interactions

A template fitting technique for reconstructing the amplitude of signals produced by the lead tungstate crystals of the CMS electromagnetic calorimeter is described. This novel approach is designed to suppress the contribution to the signal of the increased number of out-of-time interactions per beam crossing following the reduction of the accelerator bunch spacing from 50 to 25 ns at the start of Run 2 of the LHC. Execution of the algorithm is sufficiently fast for it to be employed in the CMS high-level trigger. It is also used in the offline event reconstruction. Results obtained from simulations and from Run 2 collision data (2015-2018) demonstrate a substantial improvement in the energy resolution of the calorimeter over a range of energies extending from a few GeV to several tens of GeV.Peer reviewe